اخلاق و دستورالعمل آزمایش‌های تحقیقاتی روی حیوانات

نوع مقاله : مقاله ترویجی

نویسندگان

گروه شیلات، دانشکده منابع طبیعی، دانشگاه گیلان، صومعه سرا

چکیده

بسیاری از پیشرفت‌های علمی جوامع بشری درنتیجه استفاده از حیوانات در رده‌های مختلف جانوری است. گونه‌های حیوانات متعددی برای توسعه دانش، به‌عنوان گونه مدل در علوم مختلف شناخته‌شده می‌باشند. البته این موضوع دارای اهمیت است که اصول اخلاقی و بررسی رفاه در حیوانات قبل، در حین و بعد از انجام آزمایش‌ها رعایت گردد. در این مقاله اصول سه‌گانه جایگزینی، کاهش و پالایش در انجام مطالعات پژوهشی حیوانات معرفی می‌گردد. همچنین منابع کاربردی در دسترس و معتبر دستورالعمل‌های آزمایش‌های تحقیقاتی با تأکید بر رعایت اصول اخلاق و رفاه در حیوانات ارائه می‌گردد. در انتها، به اهمیت گزارش‌دهی و همکاری بین محققین و کارکنان مراقبت از حیوانات در انجام آزمایش‌های حیوانی می‌پردازیم. با رعایت اصول اخلاقی و همچنین رسیدن به اهداف غنی‌سازی شرایط زندگی حیوانات در اسارت، اعتبار و روایی نتایج علمی در تحقیقات بیشتر خواهد بود.

کلیدواژه‌ها


عنوان مقاله [English]

Ethics and Guidelines for Research Experiments on Animals

نویسندگان [English]

  • Saeed Shafiei Sabet
  • Anahita Alizadeh
  • Maryam Kiani
Fisheries department, Faculty of natural resources, University of Guilan, Sowmeh Sara
چکیده [English]

Many of the scientific advances from human societies are the result of the use of animals across different taxa. A range of animals are used as ‘model’ species in many fields of science in order to generate new knowledge and to develop or confirm scientific theories. It is fundamentally important to consider the ethical principles of animal use, and to monitor the welfare of animals before, during and after experimental interventions. In this article, the three principles of Replacement, Reduction and Refinement for animal research are introduced. We also discuss practical and reliable existing guidelines for research experiments with an emphasis on compliance with best practice principles of animal ethics and welfare. Lastly, we discuss the importance of transparent, accurate reporting and cooperation between researchers and technicians when conducting animal experiments. The application of ethical principles and optimization of the living conditions of animals in captivity will enhance and improve the validity and reliability of scientific outcomes and progress. 

کلیدواژه‌ها [English]

  • model species
  • scientific progress
  • reproducibility
  • culture
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