نشاء علم

نشاء علم

نقش میکروب های خوب در بدن

نوع مقاله : مقاله ترویجی

نویسنده
مرکز تحقیقات بیولوژی پزشکی، پژوهشکده فناوری های سلامت، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران
چکیده
میکروب‌های متنوع و زیادی در بخش‌های مختلف بدن مانند دستگاه گوارش، دستگاه تنفسی، پوست و سایر قسمت‌ها وجود دارند که نه‌تنها بیماری‌زا نمی‌باشند، بلکه تأثیرات مثبت و ضدبیماری از خود نشان می‌دهند. در رابطه با مکانیسم‌های کلی تأثیرات مثبت میکروب‌ها، موارد متعددی مانند هضم غذا، بهبود عملکرد روده، تولید مواد مغذی، سم‌زدایی، تحریک تمایز سلولی، پیشگیری از کلونیزاسیون پاتوژن‌ها، تعدیل سیستم ایمنی و تأثیر بر محور ارتباطی روده با سایر اندام‌ها پیشنهاد شده ‌است. میکروب‌های ساکن روده که بزرگترین جامعه میکروبی بدن را تشکیل می‌دهند، علاوه‌بر نقش برجسته‌ای که در تخمیر غذا، تولید اسیدهای چرب زنجیره کوتاه، تولید ویتامین‌ها، تولید مواد زیست-فعال و محافظت در برابر پاتوژن‌ها دارند، با بروز فعل و انفعالات پیچیده با سیستم ایمنی میزبان در روده که بزرگترین اندام ایمنی محسوب می‌شود نقش قابل‌توجهی در ارتباط دوطرفه روده با سایر اندام‌ها از جمله مغز، کبد، ریه و کلیه بازی می‌کنند. در مقاله حاضر سعی شده است با پرداختن به میکروب‌های ساکن قسمت‌های مختلف بدن و بیان فواید حضور آنها برای میزبان، یک دیدکلی از وجهه مثبت حضور میکروب‌ها در بدن به خواننده ارائه شود.
کلیدواژه‌ها

عنوان مقاله English

The Role of Beneficial Microorganisms in The Body

نویسنده English

Soghra Bagheri
Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
چکیده English

A diverse range of microorganisms can be found in various regions of the body, such as the digestive tract, respiratory system, skin, and other areas. These microorganisms not only lack pathogenic characteristics but also offer advantageous effects that aid in disease prevention. Microbes exert their beneficial influence through a multitude of mechanisms, including food digestion, enhancement of gut functionality, production of nutrients, detoxification processes, stimulation of cellular differentiation, prevention of pathogen colonization, modulation of the immune system, and impact on communication between the gut and other organs. The intestinal microbes, which form the largest microbial community in the body, play a significant role in food fermentation, production of short-chain fatty acids and vitamins, generation of bioactive substances, and protection against pathogens. Additionally, they engage in intricate interactions with the immune system in the gut, which is considered the body's largest immune organ. These interactions play a crucial role in the bidirectional communication between the intestine and other organs, including the brain, liver, lung, and kidney. The purpose of this article is to provide an overview of the positive aspects of microorganisms in the body by examining the resident microorganisms in different body parts and highlighting their benefits for the host.

کلیدواژه‌ها English

Microbiota
Gut
Brain
Mouth
Lung
Butyrate
Acetate
Propionate
Cancer
Pathogen
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  • تاریخ دریافت 26 دی 1402
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  • تاریخ پذیرش 11 فروردین 1403