نشاء علم

نشاء علم

چشم اندازی از واکسن های نوترکیب خوراکی بر پایه ریز جلبک ها

نوع مقاله : مقاله ترویجی

نویسندگان
پژوهشکده آبزی پروری آب های جنوب کشور، موسسه تحقیقات علوم شیلاتی کشور، سازمان تحقیقات، آموزش و ترویج کشاورزی، اهواز، ایران
چکیده
در دهه های اخیر، بیوتکنولوژی ریزجلبکی به یکی از با ارزش ترین منابع افزودنی های کاربردی خوراک تبدیل شده است. بسیاری از ریزجلبک ها در آبزی پروری سودمند در نظر گرفته شده اند، زیرا به عنوان مکمل های غذایی توانایی های تقویت ایمنی، مقاومت در برابر بیماری های عفونی و تحمل به استرس های محیطی را افزایش می دهند و برخی از آنها غیر سمی و سرشار از آنتی اکسیدان می باشند، به طوری که می توان آنها را به عنوان یک حامل دارویی برای انسان یا حیوانات مورد بررسی قرار داد. در حال حاضر موارد موفقی از استفاده از ریزجلبک ها برای تولید واکسن های خوراکی در صنعت آبزی پروری وجود دارد. اکثر واکسن های نوترکیب بر اساس گونه Chlamydomonas reinhardti تولید می شوند. با این حال، واکسن های تجاری کمی در دسترس هستند. همچنین هنوز مشخص نیست که چگونه ریزجلبک ها یا ترکیبات زیست فعال آنها ممکن است سیگنال ها را در سیستم ایمنی گونه های آبزیان القا کنند. این مقاله با هدف جمع‌آوری تحقیقات منتشر شده در مورد پتانسیل ریزجلبک ها در تولید واکسن های نوترکیب برای آبزی پروری، می باشد. تا ایده هایی برای توسعه واکسن های خوراکی نوترکیب میکروجلبک در آینده ارائه دهد.
کلیدواژه‌ها

عنوان مقاله English

A perspective of oral recombinant vaccines based on microalgae

نویسندگان English

mehrnaz shirmohammadi
Farhanaz Kianersi
South of Iran Aquaculture Research Institute, Iranian Fisheries Science Research Institute, Agricultural Research Education and Extension Organization (AREEO), Ahvaz, Iran.
چکیده English

In recent decades, microalgae biotechnology has become one of the most valuable sources of functional feed additives. Many microalgae are considered beneficial in aquaculture, because as nutritional supplements, they increase immunity-enhancing abilities, resistance to infectious diseases, and tolerance to environmental stress. Some of them are non-toxic and rich in antioxidants, so that they can be investigated as a drug carrier for humans or animals. Currently, there are successful cases of using microalgae to produce edible vaccines in the aquaculture industry. . Most of the recombinant vaccines are produced based on Chlamydomonas reinhardtii species. However, few commercial vaccines are available. It is also unclear how microalgae or their bioactive compounds may induce signals in the immune system of aquatic species. This article aims to collect published research on the potential of microalgae in the production of recombinant vaccines for aquaculture. In order to provide ideas for the development of recombinant microalgae oral vaccines in the future.

کلیدواژه‌ها English

Aquaculture
Active compounds of microalgae
Immune system
Recombinant vaccines
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